Metformin Longevity Benefits Could Slow Down Aging

What is Metformin?

Metformin is an FDA-approved drug that is commonly used to treat patients suffering from Type 2 diabetes. It works to target several age-related mechanisms and issues and also has demonstrated protective effects against several age-related diseases. The drug was initially derived from natural compounds found in the French Lilac plant and has been used for over 60 years with an outstanding safety record. Since the Middle Ages, this drug has been used to help treat diabetes in patients. It is currently listed on the World of Health’s Essential Medicines, which is a catalog of the most cost-effective, safe, and overall effective therapies for diabetes.

Metformin can either be used alone or in combination with other medications. It helps to control the glucose levels within our bodies. In simple terms, it decreases the amount of glucose your body absorbs from its food intake as well as the glucose produced by the liver. It increases the body’s response to insulin, as well, which is why it is so beneficial when treating patients with Type 2 diabetes.

How does Metformin slow down aging?

In recent studies, metformin has been known to increase the lifespan of several different species such as rats, mice, fleas, and worms. Research is still underway about the direct benefits that Metformin has on a human’s lifespan, but it has been known to slow down the effects of aging.

Because metformin is known to lower insulin resistance, it also helps the body to regulate insulin better. Insulin resistance is directly linked to inflammation, and inflammation happens with aging. This means metformin could help to fight these inflammatory effects of aging by simply regulating our body’s insulin. Inflammation also lowers oxidative stress, which occurs when there is damage to the cells by unstable molecules, which is also a normal part of the aging process. However, the metformin longevity process lowers oxidative stress and inflammation, thus slowing down aging.

What are other benefits associated with Metformin?

According to, a company that offers prescription therapies such as metformin, there are several other unique benefits linked to taking metformin that also have anti-aging effects on the body. Listed below are a few of the benefits they discuss.

May lower risk of colon & pancreatic cancer

According to SpringerLink, studies have shown that those who use metformin as opposed to insulin were less likely to develop solid cancers. It was associated with a lower risk of cancer, primarily in the colon and pancreas.

May reduce the risk of dementia and cognitive impairment

There is strong evidence to support the importance of insulin resistance in cognitive decline and dementia. Metformin increases the body’s response to insulin to help protect users from cognitive decline.

May reduce the risk of macrovascular disease

Studies have shown that Metformin also reduces the risk of developing the macrovascular disease. Macrovascular complications are the leading cause of death for diabetics, but Metformin controls levels of blood glucose within the body by lowering insulin resistance, thus helping to prevent macrovascular disease.

Facilitates weight loss

Although Metformin isn’t a weight-loss drug, researchers have been able to find a link between the drug and weight loss. A study published in the journal Diabetic Care stated that the drug could help with treatment for excess body weight.

Reduces the chance of developing diabetes

Because Type 2 diabetes is caused by insulin resistance, Metformin is especially essential in reducing the overall chance of developing diabetes. This is because Metformin works to lower the body’s resistance to insulin.

Metformin is essential for those currently battling Type 2 diabetes. However, it also has other unique benefits for those who are non-diabetic looking to slow down aging, reduce inflammation, or those who are struggling with weight loss. If these are symptoms and issues that you are currently experiencing, Metformin may be the solution choice for you.


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